DLin-MC3-DMA is one of the most utilized ionizable cationic lipids used for gene delivery in vivo. It is used to form liposomes, lipid nanoparticles (LNPs), and other related nanodelivery systems that can encapsulate siRNA, mRNA, plasmid DNA, or small molecules for delivery into the cytoplasm and for systemic administration of gene therapies. DLin-MC3-DMA was used in the first FDA approved RNAi treatment consisting of an siRNA targeted to hepatocytes for the treatment of polyneuropathy of hATTR amyloidosis in adults. SYNONYMS: MC3, (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoateContact us at [email protected] to learn about our cGMP grade DLin-MC3-DMA manufactured under 21 CFR part 210, 211.
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Polysciences/CellVue® NIR780 Kit For Membrane Labeling - MIDI Kit/1 kit/24852-1 | 24852-1 | Cell Biology | 其他试剂 | 321.00 | Polysciences/XTT/100 mg/19661-100 | 19661-100 | Molecular Biology | 合成 | 187.00 | Polysciences/1M Glycine-HCl Buffer, pH 2.7±0.1, 10X Concentrate/500 ml/24074-500 | 24074-500 | Buffers | 其他 | 34.00 | Polysciences/Grids - Square Mesh Grids - Standard - Nickel 200mesh/10 vials/7552N-10 | 7552N-10 | Electron Microscopy | 微球标准品 | 336.00 | Polysciences//1 kg/18319-1 | 18319-1 | Monomer & Polymer Adjuncts | 单体 | 148.00 | Polysciences/Fluoresbrite® YG Carboxylate Microspheres 0.05µm/10 ml/16661-10 | 16661-10 | Polymer Microspheres | 微球 | 373.00 | Polysciences/Heparin, sodium salt (Sodium heparin, from porcine intestinal mucosa)/100M USP Units (100M/01491-100 | 01491-100 | BioReagents | 盐 | 79.00 | Polysciences/0.05M Phosphate-Citrate Buffer, pH 5.0±0.2, 1X Powdered Blend/5 pouches/24079-5 | 24079-5 | Buffers | 其它缓冲液 | 66.00 | polysciences/18879 Amino Superparamagnetic Microparticles, 1-2µmIron-containing microparticles,2.5% solids (w/v) aqueous | 18879-2 | Magnetic Microspheres and Particles | 磁珠 | 129.00 | polysciences/Monodisperse latex polystyrene Polybead beads particles microspheres flow cytometry FACS calibration bright | 23520-10 | Flow Cytometry | 荧光染料标准品 | 240.00 | polysciences/Polysciences BLI1909 Glutaraldehyde, EM Grade, 25%, electron mincroscopy, amine/10x10 ml/BLI1909-10 | BLI1909-10 | Accessory Reagents & Companion Products | 表面活性剂 | 65.00 | polysciences/Magnetic Iron Separations Immunomagnetic Particles Iron Oxide Superparamagnetic Paramagnetic Magnetic Bead | 84101S-1 | BioMag® & BioMag®Plus | 架 | 425.00 | Polysciences/Ethylene glycol diglycidyl ether (EGDGE)/10 g/01479-10 | 01479-10 | Polymers | 多聚物 | 40.00 |